Molecular Mechanisms Driving Physiology and Pathology During Aging

The Molecular Mechanisms Driving Physiology and Pathology During Aging Symposium will be held on Friday, October 7, 2022 in the 1st Floor Baldwin Auditorium located in the Lurie Biomedical Research Building, 303 East Superior Street, Chicago, IL 60611.

Registration is required to attend this one-day conference. The deadline to register is Monday, October 3, 2022. Online registration is located here. There is no charge for registration.

Symposium Organizers

This conference is organized by the investigators on the Program Project Grant (PPG) on Aging led by G.R. Scott Budinger, MD, in collaboration with William Balch, PhD, at Scripps Research Institute and Navdeep S. Chandel, PhD, Alexander V. Misharin, MD, PhD, Richard Morimoto, PhD, Karen M. Ridge, PhD, and Jacob I. Sznajder, MD, at Feinberg.

Program Description

Although the association between mitochondrial dysfunction and aging has long been recognized, the molecular mechanisms that link metabolism with aging phenotypes are only now being revealed. In this conference, leaders in the field of aging biology and metabolism will discuss the molecular and signaling pathways that underlie the relationship between organismal and cellular metabolism and age-related tissue dysfunction. The discussions will focus on therapies targeting metabolism and proteostasis that might prevent or reverse the loss of resilience in older individuals.

Speakers

	“Metabolism of aging and delayed aging by caloric restriction” Rozalyn Anderson, PhD Professor Director of Metabolism of Aging Program Department of Medicine University of Wisconsin
	“Systematic functionalization of redox-regulated protein cysteines in aging” Edward Chouchani, PhD Associate Professor of Cell Biology Harvard University
	“The aging brain microenvironment drives development of disease-associated microglia” Rogan Grant PhD Candidate Pulmonary and Critical Care Medicine Northwestern University
	“Mitochondrial integrated stress response controls lung epithelial cell fate” SeungHye Han, MD Assistant Professor Pulmonary and Critical Care Medicine Northwestern University
	“Aging and cellular and molecular biomarkers of successful responses to therapy in severe pneumonia” Alexander Misharin, MD, PhD Associate Professor Pulmonary and Critical Care Medicine Northwestern University
	“Profiling the TCR repertoire landscape during severe pneumonia” Luisa Morales-Nebreda, MD Assistant Professor Pulmonary and Critical Care Medicine Northwestern University
	“Molecular basis of metformin action” Colleen Reczek, PhD Research Assistant Professor of Medicine Pulmonary and Critical Care Medicine Northwestern University
	“Expression of cleavage resistant Mertk prevents the age-related decline in muscle function after viral pneumonia” Connie Runyan Pulmonary and Critical Care Medicine Northwestern University
	“Why diseases are tissue-specific? Lessons from mitochondrial diseases and stress responses” Anu Suomalainen-Wartiovaara, MD, PhD Academy Professor University of Helsinki, Finland
	“Transitional states in regeneration and disease” Purushothama Rao Tata, PhD Assistant Professor Departments of Cell Biology and Medicine Co-Director, Duke Regeneration Center Duke University
	“Introducing the Potocsnak Longevity Institute at Feinberg School of Medicine” Douglas Vaughan, MD Irving S. Cutter Professor and Chair, Department of Medicine Director, Potocsnak Longevity Institute Northwestern University

Funding for this scientific conference on aging is provided by the National Institute on Aging PPG award 1P01AG049665.

Registration

Registration is required. Please click here to register for this meeting. The registration deadline is Monday, October 3, 2022 at 11:59 PM.

If you have problems accessing the link, please email Sean Campbell at seancampbell@northwestern.edu.

Schedule

Download the complete program here.

9:00 AM -	Morning Session Begins
1:15 PM -	Afternoon Session Begins
5:00 PM -	Reception

Accommodations

There are several hotels that are within walking distance of the conference venue:

AC Hotel by Marriott, 630 North Rush, Chicago, IL 60611

Aloft Chicago Mag Mile, 243 East Ontario, Chicago, IL 60611

Courtyard by Marriott, 165 East Ontario, Chicago, IL 60611

DoubleTree by Hilton, 300 East Ohio, Chicago, IL 60611

Embassy Suites, 511 North Columbus Drive, Chicago, IL 60611

Embassy Suites, 600 North State Street, IL 60654

Hampton Inn, 160 East Huron, Chicago, IL 60611

Homewood Suites, 152 East Huron, Chicago, IL 60611

Hyatt Centric Chicago, 633 North St. Clair, Chicago, IL 60611

Omni Hotel, 676 North Michigan Avenue, Chicago, IL 60611

W Chicago, 644 North Lake Shore Drive, Chicago, IL 60611

Warwick Allerton, 701 North Michigan Avenue, Chicago, IL 60611

Public Transportation

During rush hour (7-9 AM and 4-6 PM) or inclement weather: The Chicago Transit Authority (CTA) offers train service to/from both O’Hare and Midway airports and can be the most reliable way to reach our campus.

During non-peak travel times: Taxis or ride sharing services are also good options to travel to our campus.

CTA Service

You will need a Ventra Card to use the train and bus in Chicago. You can purchase a card online or at any CTA station. The fare is $5 for the train from O’Hare and $0.25 for the bus transfer (used within 2 hours of original fare).

Route from O'Hare

From O’Hare International Airport Terminals 1, 2, or 3, follow signs that say “CTA Trains” or “Trains to City” which will take you to the O’Hare Blue Line station on the lower level.
Take the Blue Line train to the Clark/Lake station to transfer to the Red Line. From the Red Line station at Lake, take the Red Line train heading north to the Howard station. Get off at the Chicago station (second stop). Go east on Chicago Avenue to Michigan Avenue, then head south to the street of your hotel. (Superior, Huron, or Erie Street, ~0.3 miles)

From O’Hare International Airport Terminals 1, 2, or 3, follow signs that say “CTA Trains” or “Trains to City” which will take you to the O’Hare Blue Line station on the lower level.
Take the Blue Line train and get off at the Chicago station. Take the CTA Bus #66 east to Navy Pier. Get off at the Superior, Huron, or Erie stop, depending on your hotel.

Route from Midway

From Midway International Airport, follow signs that say “CTA Trains” or “Trains to City” which will take you to the Midway Orange Line station located on the east side of the airport.
Take the Orange Line train to the State/Lake station to transfer to the Red Line. From the Red Line station at Lake, take the Red Line train heading north to the Howard station. Get off at the Chicago station (second stop). Go east on Chicago Avenue to Michigan Avenue, then head south to the street of your hotel. (Superior, Huron, or Erie Street, ~0.3 miles)

Campus Shuttle Bus Service

The Intercampus Shuttle runs between the Chicago and Evanston campus on Monday through Friday.

Campus Map

Campus Map (pdf)

Interactive Map (Google Maps)